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Green tea extract

Green tea extract enhances parieto-frontal connectivity
during working memory processing

Psychopharmacology (2014) 231:3879–3888

André Schmidt & Felix Hammann & Bettina Wölnerhanssen &
Anne Christin Meyer-Gerspach & Jürgen Drewe &
Christoph Beglinger & Stefan Borgwardt
Received: 7 January 2014 /Accepted: 26 February 2014 /Published online: 19 March 2014

Introduction
Recent research indicates that green tea extract or its main
ingredients has a beneficial impact on cognitive functioning in
humans. For instance, it has been demonstrated that the consumption
of green tea improved memory and attention in
subjects with mild cognitive impairments (Park et al. 2011)
and that the consumption of flavonoid-rich foods such as
green tea reduced beta-amyloid-mediated cognitive impairments
in Alzheimer transgenic mice, suggesting a potential
therapeutic utility in dementia (Rezai-Zadeh et al. 2008;
Williams and Spencer 2012). Furthermore, higher consumption
of green tea has also been associated with a lower prevalence
of cognitive impairments in older adults (Kuriyama
et al. 2006). Comparable resultswere obtained in another study
investigating the association between green tea consumption
and cognition in 2,501 people aged over 55 years by showing
that the intake of green tea was significantly related to a lower