Anisocoria is an uncommon but well-documented early sign of nervous system dysfunction in cases of superficial siderosis. The pupils of both eyes are uneven or unequal in size greater than 0.4mm. It is an indication of optic nerve involvement and often a person will not realize it’s happening until someone notices it and points it out. Anisocoria doesn’t require treatment, does not cause pain or affect vision.
Anisocoria– Unequal Pupil Size
Sources: Superficial siderosis is a rare neurologic disease characterized by progressive sensorineural hearing lossOverview Progressive hearing loss will affect 95% of Superfi... More, cerebellar ataxiaOverview Ataxia is considered a symptom of your superficial ... More, pyramidal signs, and neuroimaging findings revealing hemosiderin deposits in the spinal and cranial leptomeninges and subpial layer. The disease progresses slowly, and patients may present with mild cognitive impairmentOverview Cognition is the range of high-level brain function... More, nystagmusOverview Nystagmus involves the involuntary and uncontrolled... More, dysmetria, spasticityOverview Spasticity is a condition in which individual muscl... More, dysdiadochokinesiaOverview Dysdiadochokinesia (DDK) is the medical term used t... More, dysarthriaOverview Cerebellar dysarthria is a distinct speech disorder... More, hyperreflexiaOverview Autonomic Hyperreflexia is a condition in which you... More, and Babinski signs. Additional features reported include dementiaOverview Dementia is the progressive decline of cognitive fu... More, urinary incontinence, anosmia, ageusia, and anisocoria. Superficial siderosis MedGen UID: 831707 •Concept ID: CN226971 •Finding Orphanet: ORPHA247245
