Superficial Siderosis patients who suffer from cerebellar atrophy induced ataxia will feel excessive fatigue just from going about your normal daily activities. A person suffering from ataxia has to fight their own body to perform regular movements. This impairment of cerebellar regulation of coordinated movement triggers increased fatigue because you are continually forced to exert more effort.
Your gait is compromised, so it takes all your concentration to keep your balance and try to walk in a reasonably straight path. You spend your whole day trying to make your body comply; you consciously have to exert muscle and coordination control, so you feel real physical and mental fatigue.
Depression is one of the most common symptoms of Superficial Siderosis patients. The connection between depression and physical fatigue is well documented. It can become an unintended cycle, constant exhaustion causes a deeper depression¹. Deep depression exacerbates fatigue.
One more contributing factor to the total exhaustion so common among Superficial Siderosis is the combination of prescription medications so many patients face every day.