Chronic Fatigue


Superficial Siderosis patients who suffer from cerebellar atrophy induced ataxia will feel excessive fatigue just from going about your normal daily activities. A person suffering from ataxia has to fight their own body to perform regular movements. This impairment of cerebellar regulation of coordinated movement triggers increased fatigue because you are continually forced to exert more effort.

Why Am I So Exhausted?

Your gait is compromised, so it takes all your concentration to keep your balance and try to walk in a reasonably straight path. You spend your whole day trying to make your body comply; you consciously have to exert muscle and coordination control, so you feel real physical and mental fatigue.

Depression is one of the most common symptoms of Superficial Siderosis patients. The connection between Depression and physical fatigue is well documented. It can become an unintended cycle, constant exhaustion causes a deeper depression¹. Deep Depression exacerbates fatigue.

An additional contributing factor to the total exhaustion so common among Superficial Siderosis patients is the combination of prescription medications so many patients face every day. Multiple prescription medications with a shared side effect of drowsiness will not help the situation.

Sleep apnea has also been found to be an underlying condition in many patients fighting ataxia. It is important to consult with a sleep clinic



Updated: November 5, 2020
¹Innov Clin Neurosci. 2011 Oct; 8(10): 40–43. Published online 2011 Oct. PMCID: PMC3225130 PMID: 22132370
Fatigue as a Residual Symptom of Depression
Steven D. Targum, MD corresponding author and Maurizio Fava, MD
Sources: Superficial siderosis is a rare neurologic disease characterized by progressive sensorineural hearing loss, cerebellar ataxia, pyramidal signs, and neuroimaging findings revealing hemosiderin deposits in the spinal and cranial leptomeninges and subpial layer. The disease progresses slowly, and patients may present with mild cognitive impairment, nystagmus, dysmetria, spasticity, dysdiadochokinesia, dysarthria, hyperreflexia, and Babinski signs. Additional features reported include dementia, urinary incontinence, anosmia, ageusia, and anisocoria. Superficial siderosis MedGen UID: 831707 •Concept ID: CN226971 •Finding Orphanet: ORPHA247245
Living With SuperficialSiderosis Website PubMed Reference Library 

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