Green tea consumption and cognitive function: a cross-sectional study from the Tsurugaya Project1–3 Shinichi Kuriyama, Atsushi Hozawa, Kaori Ohmori, Taichi Shimazu, Toshifumi Matsui, Satoru Ebihara, Shuichi Awata,Ryoichi Nagatomi, Hiroyuki Arai, and Ichiro Tsuji ABSTRACT Background: Although considerable experimental and animal evidence shows that green tea may possess potent activities of neuroprotection, neurorescue, and amyloid precursor protein processing that may lead to cognitive enhancement, no human data are available. Objective: The objective was to examine the association between green tea consumption and cognitive function in humans. Design: We analyzed cross-sectional data from a community-based Comprehensive Geriatric Assessment (CGA) conducted in 2002. The subjects were 1003 Japanese subjects aged 70 y. They completed a self-administered questionnaire that included questions about the frequency of green tea consumption. We evaluated cognitive function by using the Mini-Mental State Examination with cutoffs of28,26, and24 and calculated multivariate-adjusted odds ratios (ORs) of cognitive impairment. Results: Higher consumption
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