Anti-Inflammatory Properties of Arnica


In traditional medicine, alcoholic preparations from flowers
of Arnica montana and Arnica chamissonis ssp. foliosa are
applied externally to treat hematomas, contusions, sprains,
rheumatic diseases, and superficial inflammations of the skin.
The secondary metabolites that mediate the anti-inflammatory
effects are sesquiterpene lactones of the 10a-methylpseudoguaianolide
type like helenalin, 11a,13-dihydrohelenalin, chamissonolid,
and their ester derivatives (1–3). Several studies have
investigated how these natural compounds exert their antiinflammatory

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